منابع مشابه
Role of cell-mediated immunity in tumor eradication by hyperthermia.
A single hyperthermic treatment (44.5 degrees for 20 min) which results in successful local control of a 7-day intradermally growing fibrosarcoma in intact mice fails to permanently control tumor growth in immunodeficient nu/nu (BALB/c) or immunosuppressed (whole-body radiation, 500 rads) mice. Studies were designed to determine whether humoral or cellular-mediated factors were responsible. Nud...
متن کاملHyperthermia and immunity. A brief overview.
After many years, hyperthermia (HT) is experiencing a new resurgence as seen by the positive results of many randomized trials all over the world. Tumour immunity similarly is suggested as the fourth modality of therapy for metastatic tumours from renal carcinoma and melanoma. An overwhelming amount of data from animal models and human patients indicate that whole body and locoregional hyperthe...
متن کاملAntitumor immunity by magnetic nanoparticle-mediated hyperthermia.
Magnetic nanoparticle-mediated hyperthermia (MNHT) generates heat to a local tumor tissue of above 43°C without damaging surrounding normal tissues. By applying MNHT, a significant amount of heat-shock proteins is expressed within and around the tumor tissues, inducing tumor-specific immune responses. In vivo experiments have indicated that MNHT can induce the regression of not only a local tum...
متن کاملTumor Immunity
In a consideration of tumor immunity it appears desirable to discuss resistance to spontaneous tumors and to implanted tumor separately. Although results obtained with experimentally implanted tumors have contributed to the biology of tumors, these results can not be applied directly to spontaneous tumors and this is especially true with respect to immunity. It has long been recognized that imm...
متن کاملTumor-binding antibodies and tumor immunity
The remarkable capacity of the immune system to distinguish self from non-self makes it almost impossible to transmit cancers (or organs) from one individual to another in the absence of immunosuppressive drugs. Whereas rejection of donor cells bearing mismatched MHC alleles has been ascribed to direct activation of T cells by the altered MHC-peptide structures, the factors that initiate reject...
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ژورنال
عنوان ژورنال: Cancers
سال: 2021
ISSN: 2072-6694
DOI: 10.3390/cancers13112507